PSP-0119, CAS [[3104855-98-0]]

Produktübersicht

• Artikelname: PSP-0119, CAS [[3104855-98-0]]
• Artikelnummer: MCE-HY-179094
• Hersteller Artikelnummer: HY-179094
• Alternativnummer: MCE-HY-179094-50MG, MCE-HY-179094-5MG, MCE-HY-179094-10MG, MCE-HY-179094-25MG, MCE-HY-179094-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PSP-0119 is a highly efficient and effective PROTAC degrader targeting IRAK4 (IC50 = 2.83 nM). PSP-0119 can inhibit IRAK4 kinase activity, NF-kappabeta activity, and IL-1beta-induced IRAK4 phosphorylation. PSP-0119 degrades IRAK4 in FLT3-mutant AML cell lines, sparing FLT3-wild-type AML cells, FLT3-wild-type samples, and normal bone marrow. PSP-0119 downregulates alpha-enolase (eNOS) of MOLM-13 cells. PSP-0119 can be used for the study of Acute Myeloid Leukemia (AML)[1].

Produkteigenschaften

• Molekulargewicht: 733.77
• Reinheit: 98.6500
• CAS Nummer: [3104855-98-0]
• Formel: C38H39N9O7
• Target-Kategorie: Enolase,IRAK,NF-kappaB,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1