UNC10062 is a dopamine D1 receptor (D1R) positive allosteric modulator. UNC10062 specifically binds to the extracellular allosteric pocket (upper pocket) at the interface of transmembrane helices (TM) 1 and 7 of D1R. UNC10062 can increase dopamine potency and D1R-mediated cAMP production. UNC10062 can be used for the research of neurological disease, such as Parkinsons disease[1].
Molekulargewicht:
401.48
Formel:
C20H23N3O4S
Target-Kategorie:
Dopamine Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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