CHF-6333 is a neutrophil elastase (NE) inhibitor (IC50 = 0.21 nM, KD = 0.16 nM). CHF-6333 retains its activity in both human (IC50 = 0.22 nM) and rat (IC50 = 3.63 nM) proteases. CHF-6333 exhibits inhibitory activity against Proteinase 3 (IC50 = 22 nM). CHF-6333 can be used for the study of bronchiectasis (BE)[1].
Molekulargewicht:
764.75
Formel:
C38H39F3N6O8
Target-Kategorie:
Elastase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
