XMU-MP-10, CAS [[2251132-02-0]] Preis auf Anfrage

Artikelnummer: MCE-HY-179570
Artikelname: XMU-MP-10, CAS [[2251132-02-0]] Preis auf Anfrage
Artikelnummer: MCE-HY-179570
Hersteller Artikelnummer: HY-179570
Alternativnummer: MCE-HY-179570-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
XMU-MP-10 is a selective NEDD4 inhibitor with a KD of 43.92 nM. XMU-MP-10 selectively inhibits NEDD4 auto-ubiquitination without affecting other ubiquitination activity, upregulates of beta-TrCP and results YAP degradation without affecting NEDD4 protein expression. XMU-MP-10 exhibits significant in vivo efficacy in inhibiting TNBC tumor growth by enhancing CD8+ T cell infiltration. XMU-MP-10 enhances antitumor immune responses through the beta-TrCP/YAP/ECM axis. XMU-MP-10 can be used for Triple-Negative Breast Cancer (TNBC) research[1].
Molekulargewicht: 396.24
CAS Nummer: [2251132-02-0]
Formel: C18H14BrN5O
Target-Kategorie: E1/E2/E3 Enzyme
Anwendungsbeschreibung: MCE Product type: Reference compound