ZIP14-IN-1, CAS [[1048-17-5]]

Produktübersicht

• Artikelname: ZIP14-IN-1, CAS [[1048-17-5]]
• Artikelnummer: MCE-HY-179571
• Hersteller Artikelnummer: HY-179571
• Alternativnummer: MCE-HY-179571-25MG,MCE-HY-179571-10MG,MCE-HY-179571-5MG,MCE-HY-179571-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PPTD

Produktbeschreibung

ZIP 14-IN-1 (PPTD) is a selective and orally active ZIP14 inhibitor. ZIP 14-IN-1 inhibits ZIP14 while sparing ZIP8 (SLC39A8). ZIP 14-IN-1 efficiently blocks ZIP14-mediated uptake of multiple divalent metals (zinc, iron, manganese and cadmium). ZIP 14-IN-1 binds to a pocket formed at the dimer interface of ZIP14, obstructing the metal transport pathway. ZIP 14-IN-1 effectively reverses the consequent elevation of reactive oxygen species (ROS) and lipid peroxidation, attenuating metal-induced cytotoxicity. ZIP 14-IN-1 can be uses for cancer cachexia research[1].

Produkteigenschaften

• Molekulargewicht: 335.44
• Reinheit: 99.82
• CAS Nummer: [1048-17-5]
• Formel: C21H25N3O
• Target-Kategorie: Ferroptosis,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound