COX-2-IN-61 is an orally active COX-2 inhibitor with an IC50 of 22 µM, also inhibits COX-1 with an IC50 of 43 µM. COX-2-IN-61 exhibits anti-inflammation effects in a Carrageenan (HY-125474) induced rat paw edema model, with promising safety profiles. COX-2-IN-61 can be used for the research of inflammation[1].
Molekulargewicht:
347.41
Formel:
C15H13N3O3S2
Target-Kategorie:
COX
Anwendungsbeschreibung:
MCE Product type: Reference compound
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