KGA-4066 is a novel non-ATP-competitive CDK2 inhibitor. KGA-4066 inhibits CDK2/Cyclin A2 with an IC50 value of 236.7 nM, disrupts their interaction, promots CDK2 degradation via the lysosomal pathway. KGA-4066 has anticancer activity against hepatocellular carcinoma[1].
Molekulargewicht:
513.06
Formel:
C30H37ClO5
Target-Kategorie:
CDK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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