PLAGL2-IN-1, CAS [[3099026-16-8]] Preis auf Anfrage
Artikelnummer:
MCE-HY-180281
Hersteller Artikelnummer:
HY-180281
Alternativnummer:
MCE-HY-180281-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
PLAGL2-IN-1 is a inhibitor of pleiomorphic adenoma-like protein 2 (PLAGL2) with a Kd of 2.23 µM. PLAGL2-IN-1 suppresses PLAGL2 transcriptional activity, induces G0/G1 cell cycle arrest, and apoptosis, thereby inhibiting hepatocellular carcinoma (HCC) cell proliferation. PLAGL2-IN-1 disrupts extracellular matrix organization and suppresses the PI3K-AKT pathway by reducing AKT phosphorylation. PLAGL2-IN-1 inhibits tumor growth in an HCCLM3 xenograft mouse model. PLAGL2-IN-1 can be used for the research of HCC[1].
Molekulargewicht:
632.60
CAS Nummer:
[3099026-16-8]
Formel:
C30H35Cl2N5O4S
Target-Kategorie:
Akt,Apoptosis,PI3K,Zinc Finger Protein
Anwendungsbeschreibung:
MCE Product type: Reference compound
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