TG2-IN-3h (Compound 3h) is a transglutaminase (TG2) inhibitor (hTG2: IC50 = 6nM). TG2-IN-3h inhibits endothelial cell migration and angiogenesis. TG2-IN-3h alleviates renal fibrosis in a mouse model of hypertensive nephropathy. TG2-IN-3h can be used in research on metabolic diseases such as hypertensive nephropathy and cardiovascular and cerebrovascular diseases such as pathological angiogenesis[1].
Molekulargewicht:
430.52
CAS Nummer:
[1592640-75-9]
Formel:
C21H26N4O4S
Target-Kategorie:
Glutaminase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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