YM580 is a potent, orally active and selective Androgen Receptor (AR) antagonist (IC50 = 0.11 µM, hAR Ki = 4.6 nM, rAR Ki = 6.2 nM). YM580 exhibits good selectivity over PR, GR, and ERalpha (Kis > 3300 nM). YM580 decreases ventral prostate weight in mature intact rats dose-dependently without affecting serum testosterone levels. YM580 can be used for the research of prostate cancer[1].
Molekulargewicht:
471.41
CAS Nummer:
[262295-11-4]
Formel:
C21H19F6N5O
Target-Kategorie:
Androgen Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
