MGMT-IN-1 (Compound 2) is a light-activated MGMT inhibitor. MGMT-IN-1 can effectively enhance the cytotoxicity of Temozolomide (TMZ) (HY-17364) only under light conditions, significantly increasing the DNA damage caused by TMZ. MGMT-IN-1 can be used for the study of chordoma[1].
Molekulargewicht:
521.34
Formel:
C19H17BrN6O5S
Target-Kategorie:
DNA Methyltransferase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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