QND8 is a selective and potent alpha7 nicotinic acetylcholine receptor (nAChR) agonist. QND8 can alleviate thermal hyperalgesia and mechanical hyperalgesia in carrageenan-induced inflammatory pain mouse model. QND8 can reduce the swelling of the mice feet, inhibit the release of pro-inflammatory factors at the inflammatory site, and prevent the infiltration of white blood cells. QND8 can be used for the research of inflammation and neurological disease, such as arthritis[1].
Molekulargewicht:
270.33
CAS Nummer:
[1778682-60-2]
Formel:
C15H18N4O
Target-Kategorie:
nAChR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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