LOXL2/sGC modulator-2 Preis auf Anfrage

Artikelnummer: MCE-HY-180585
Artikelname: LOXL2/sGC modulator-2 Preis auf Anfrage
Artikelnummer: MCE-HY-180585
Hersteller Artikelnummer: HY-180585
Alternativnummer: MCE-HY-180585-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
LOXL2/sGC modulator-2 (Compound 9k) is a selective and orally active lysyl oxidase-like 2 (LOXL2) and soluble guanylate cyclase (sGC) dual-target regulator. LOXL2/sGC modulator-2 shows inhibitory activity for LOXL2 with an IC50 of 0.1 µM and can activate sGC. LOXL2/sGC modulator-2 can ameliorate vascular remodeling and reduce pulmonary artery pressure. LOXL2/sGC modulator-2 can downregulate PKG1, PCNA, alpha-SMA, collagen I and fibronectin levels. LOXL2/sGC modulator-2 can be used for the research of pulmonary arterial hypertension [1].
Molekulargewicht: 487.47
Formel: C25H24F3N3O4
Target-Kategorie: Collagen,Guanylate Cyclase,Monoamine Oxidase,PKG
Anwendungsbeschreibung: MCE Product type: Reference compound