Triphenyltin(IV) diisopropyl dithiocarbamate Preis auf Anfrage
Artikelnummer:
MCE-HY-180782
Hersteller Artikelnummer:
HY-180782
Alternativnummer:
MCE-HY-180782-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Triphenyltin(IV) diisopropyl dithiocarbamate (Compound OC2) is an anti-leukemia agent. Triphenyltin(IV) diisopropyl dithiocarbamate exhibits extremely strong cytotoxicity towards Jurkat cells, with an IC50 value of 0.1 µM. Triphenyltin(IV) diisopropyl dithiocarbamate causes DNA damage, which subsequently leads to mitochondrial dysfunction, a large amount of ROS production, and ultimately results in the activation of the mitochondrial apoptosis pathway (involving the activation of Caspase-9/-3) and the G0/G1 phase cell cycle arrest, all of which jointly lead to the death of leukemia cells[1].
Molekulargewicht:
526.34
Formel:
C25H29NS2Sn
Target-Kategorie:
Apoptosis,Caspase,DNA/RNA Synthesis,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
