NT32 is a selective METTL13 stabilizer with a Kd value of 14 µM. NT32 could occupy both the SAM/SAH-binding pocket and the peptide substrate-binding site of METTL13 simultaneously. NT32 specifically targets and stabilizes METTL13. NT32 shows no inhibitory activity against non-small cell lung cancer[1].
Molekulargewicht:
1045.14
Formel:
C42H64N18O12S
Target-Kategorie:
Histone Methyltransferase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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