Factor B-IN-8, CAS [[3049710-19-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: Factor B-IN-8, CAS [[3049710-19-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-181040
• Hersteller Artikelnummer: HY-181040
• Alternativnummer: MCE-HY-181040-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Factor B-IN-8 (Compound (3R ,4R )-15) is a potent, selective and orally active factor B inhibitor with an IC50 of 10.2 nM. Factor B-IN-8 can effectively inhibit the binding of factor B to C3b and the subsequent formation of C3 convertase (C3bBb). Factor B-IN-8 can inhibit the deposition of membrane attack complex (MAC) mediated by alternativepathway with an IC50 of 59.3 nM. Factor B-IN-8 can reduce the cleavage of factor B protein and decrease the deposition of complement C3d in the glomeruli and renal tubules. Factor B-IN-8 can be used for researches of arthritis and paroxysmal nocturnal hemoglobinuria (PNH)[1].

Produkteigenschaften

• Molekulargewicht: 462.46
• CAS Nummer: [3049710-19-9]
• Formel: C24H25F3N2O4
• Target-Kategorie: Complement System

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound