PLK1-IN-16, CAS [[3068378-51-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-181051
Hersteller Artikelnummer:
HY-181051
Alternativnummer:
MCE-HY-181051-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
PLK1-IN-16 is a selective polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.25 nM. PLK1-IN-16 exhibits lower inhibitory potency against PLK2 and PLK3, induces G2 phase cell cycle arrest, induces apoptosis, and exhibits antiproliferative activity against tumor cells. PLK1-IN-16 can be stable under simulated gastric acid environmental conditions, and acceptable CYP 450 inhibition. PLK1-IN-16 can be used for the study of triple-negative breast cancer (TNBC), breast cancer, leukemia[1].
Molekulargewicht:
526.65
CAS Nummer:
[3068378-51-5]
Formel:
C26H34N6O4S
Target-Kategorie:
Apoptosis,Polo-like Kinase (PLK)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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