POLRMT-IN-3 is a photosensitive inhibitor of mitochondrial RNA polymerase (POLRMT). POLRMT-IN-3 is biologically inactive in the dark but rapidly releases the active parent compound LJ03 upon illumination with 405 nm light, enabling spatiotemporally precise inhibition of POLRMT. POLRMT-IN-3 exhibits antitumor activity and can be used in research on tumors such as pancreatic cancer and ovarian cancer[1].
Molekulargewicht:
635.64
Formel:
C36H30FN3O7
Target-Kategorie:
Drug Intermediate
Anwendungsbeschreibung:
MCE Product type: Reference compound
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