AMPKalpha1 activator 1 is a selective and orally active AMPKalpha1 activator with an EC50 of 35.1 nM. AMPKalpha1 activator 1 shows 176-fold selectivity over AMPKalpha2. AMPKalpha1 activator 1 can be used as a cell protectant and a kidney protectant. AMPKalpha1 activator 1 attenuates elevation of serum creatinine and blood urea nitrogen levels, alleviates kidney damage, and reduces cellular infiltration in renal ischemia-reperfusion injury contexts. AMPKalpha1 activator 1 can be associated with renal ischemia-reperfusion injury research[1].
Molekulargewicht:
453.94
Formel:
C22H20ClN5O2S
Target-Kategorie:
AMPK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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