VU6083859 is a blood-brain barrier-permeable TAOK1 inhibitor with an IC50 of 158 nM. VU6083859 selectively inhibits TAOK1, exhibits only weak or no activity against TAOK2 and TAOK3, and shows high selectivity for a variety of other kinases. VU6083859 is applicable to research related to neurodevelopmental disorders and tauopathies.
Molekulargewicht:
467.48
Formel:
C26H24F3N3O2
Target-Kategorie:
MAP3K
Anwendungsbeschreibung:
MCE Product type: Reference compound
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