WWZ-11-098

Produktübersicht

• Artikelname: WWZ-11-098
• Artikelnummer: MCE-HY-181490
• Hersteller Artikelnummer: HY-181490
• Alternativnummer: MCE-HY-181490-50MG, MCE-HY-181490-25MG, MCE-HY-181490-5MG, MCE-HY-181490-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

WWZ-11-098 is a selective CDK6 PROTAC degrader with DC50 of 2.6 nM. WWZ-11-098 induces degradation of CDK6 in a CRBN-dependent manner, while sparing CDK1, CDK2, CDK4, and CDK9. WWZ-11-098 induces apoptosis, G1-S cell cycle arrest and shows anti-proliferative activity in cancer cells. WWZ-11-098 exhibits antitumor efficacy in a xenograft model without signs of toxicity. WWZ-11-098 can be used for the research of leukemia[1].

Produkteigenschaften

• Molekulargewicht: 828.90
• Formel: C39H47F3N8O7S
• Target-Kategorie: Apoptosis,CDK,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound