Snail IN-1, CAS [[3083216-69-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-181654
Hersteller Artikelnummer:
HY-181654
Alternativnummer:
MCE-HY-181654-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Snail IN-1 is an orally active Snail inhibitor with a Ka of 0.36 µM.Snail IN-1 disrupts Snail-CBP interaction, accelerates Snail protein degradation, reduces Snail acetylation, increases Snail polyubiquitination, and selectively downregulates Snail protein without altering other EMT transcription factors.Snail IN-1 reduces atherosclerotic plaque burden, modulates inflammation and plaque stability factors, downregulates CCL5, CXCL10, MMP2, and MMP9, and upregulates alpha-smooth muscle actin.Snail IN-1 exerts anti-inflammatory and plaque-stabilizing properties.Snail IN-1 can be used for the research of atherosclerosis[1].
Molekulargewicht:
409.50
CAS Nummer:
[3083216-69-4]
Formel:
C21H23N5O2S
Target-Kategorie:
CXCR,Epigenetic Reader Domain,MMP
Anwendungsbeschreibung:
MCE Product type: Reference compound
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