Prexasertib (dihydrochloride), CAS [[1234015-54-3]]

Produktübersicht

• Artikelname: Prexasertib (dihydrochloride), CAS [[1234015-54-3]]
• Artikelnummer: MCE-HY-18174A
• Hersteller Artikelnummer: HY-18174A
• Alternativnummer: MCE-HY-18174A-10MMX1ML,MCE-HY-18174A-100MG,MCE-HY-18174A-5MG,MCE-HY-18174A-50MG,MCE-HY-18174A-10MG,MCE-HY-18174A-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: LY2606368 (dihydrochloride)

Produktbeschreibung

Prexasertib dihydrochloride (LY2606368 dihydrochloride) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of 50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dihydrochloride causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dihydrochloride shows potent anti-tumor activity[1][2].

Produkteigenschaften

• Molekulargewicht: 438.31
• Reinheit: 99.73
• CAS Nummer: [1234015-54-3]
• Formel: C18H21Cl2N7O2
• Target-Kategorie: Apoptosis,Checkpoint Kinase (Chk)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound