IMP-Zn is a pyrazole-hydrazone Schiff base zinc (II) complex. IMP-Zn exhibits significant antiproliferative activity against human colorectal cancer cells and induces cell cycle arrest. IMP-Zn shows stronger binding affinity than its free ligand IMP towards three cancer-related protein targets: EGFR kinase 1M17, cytochrome P450 3RUK, and CDK inhibitor 6GUE. IMP-Zn can be used in studies related to colorectal cancer[1].
Molekulargewicht:
441.62
Formel:
C17H15Cl2N5OZn
Target-Kategorie:
CDK,Cytochrome P450,EGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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