IDO1/TDO-IN-11 (Compound Y-13) is a dual IDO1 and TDO inhibitor, with an IC50 of 2.87 µM against hIDO1 and an IC50 of 0.08 µM against hTDO. IDO1/TDO-IN-11 inhibits NO production and ROS production. IDO1/TDO-IN-11 alleviates cellular neuroinflammatory damage and ameliorates Parkinsons disease. IDO1/TDO-IN-11 is applicable to research related to Parkinsons disease[1].
Molekulargewicht:
309.32
Formel:
C18H15NO4
Target-Kategorie:
Indoleamine 2,3-Dioxygenase (IDO),NO Synthase,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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