NEURL1B-IN-1, CAS [[3068938-30-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-182008
Hersteller Artikelnummer:
HY-182008
Alternativnummer:
MCE-HY-182008-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
NEURL1B-IN-1 is a NEURL1B degrader with a Kd value of 46.2 nM. NEURL1B-IN-1 binds to Arg422 within the NHR2 domain of NEURL1B, triggers its autoubiquitination and proteasomal degradation, disrupts its interaction with DLL1, and attenuates the Notch signaling pathway. NEURL1B-IN-1 induces cell cycle arrest and apoptosis, and inhibits migration of hepatocellular carcinoma cells. NEURL1B-IN-1 is applicable to research related to hepatocellular carcinoma[1].
Molekulargewicht:
478.62
CAS Nummer:
[3068938-30-4]
Formel:
C30H38O5
Target-Kategorie:
Apoptosis,Caspase,Notch,PARP
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten