YL0441 is an inhibitor of deltaFOSB/JUND heterodimers and deltaFOSB homomultimers, with IC50 values of 13.7 µM and 12.3 µM, respectively. YL0441 blocks the binding of deltaFOSB to DNA. YL0441 reduces deltaFOSB bound to genomic DNA in the hippocampal tissues of APP mice. YL0441 is applicable to the research of Alzheimers disease[1].
Molekulargewicht:
385.39
Formel:
C19H15NO6S
Target-Kategorie:
AP-1,DNA Alkylator/Crosslinker
Anwendungsbeschreibung:
MCE Product type: Reference compound
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