BDM71230 is an orally active inducer of insulin-degrading enzyme (IDE), with an EC50 of 1.9 µM against human IDE. BDM71230 binds to the interface of IDE dimers and enhances the catalytic activity of IDE via steric effects. BDM71230 can potentiate the hydrolytic effect of IDE on insulin and slightly attenuate the hypoglycemic effect of insulin. BDM71230 serves as a pharmacological tool for investigating IDE function and is applicable to studies related to glucose intolerance[1].
Molekulargewicht:
431.51
Formel:
C25H26FN5O
Target-Kategorie:
Insulin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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