PI3K/AKT-IN-6 is an orally effective PI3K/AKT signaling pathway inhibitor and anti-inflammatory agent. PI3K/AKT-IN-6 inhibits the production of pro-inflammatory cytokines TNF-alpha and IL-6, and downregulates the expression of inflammatory mediators COX-2 and iNOS. PI3K/AKT-IN-6 improves related symptoms in colitis mice. PI3K/AKT-IN-6 can be used for the research of inflammatory diseases such as colitis[1].
Molekulargewicht:
499.36
Formel:
C23H25Cl2FN2O5
Target-Kategorie:
Akt,COX,Interleukin Related,NO Synthase,PI3K
Anwendungsbeschreibung:
MCE Product type: Reference compound
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