SBI-0802767 is an orally active, uncompetitive and highly selective inhibitor of protein tyrosine phosphatase (LMPTP) with an IC50 of 0.239 µM. SBI-0802767 exhibits >1000-fold selectivity over other protein tyrosine phosphatases and enhances insulin signaling in hepatocytes. SBI-0802767 is used in studies of obesity-related type 2 diabetes and insulin resistance[1].
Molekulargewicht:
294.14
CAS Nummer:
[68220-27-9]
Formel:
C12H9Cl2N5
Target-Kategorie:
Phosphatase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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