(S,S)-SARM1-IN-9, CAS [[3020765-70-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: (S,S)-SARM1-IN-9, CAS [[3020765-70-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-182500A
• Hersteller Artikelnummer: HY-182500A
• Alternativnummer: MCE-HY-182500A-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

(S,S)-SARM1-IN-9 (Compound MY-13A) is a stereoselective SARM1 inhibitor with covalent binding properties. (S,S)-SARM1-IN-9 covalently modifies Cys311 in the autoregulatory ARM domain of wild-type SARM1, thereby blocking NADase activity, without inhibiting the SARM1C311A or SARM1C311S mutants. (S,S)-SARM1-IN-9 blocks vacor- and vincristine-induced axon degeneration in primary rodent dorsal root ganglion neurons. (S,S)-SARM1-IN-9 can be used for research on axon degeneration-dependent neurological disorders, including chemotherapy-induced peripheral neuropathy[1].

Produkteigenschaften

• Molekulargewicht: 427.45
• CAS Nummer: [3020765-70-9]
• Formel: C25H21N3O4
• Target-Kategorie: Toll-like Receptor (TLR)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound