Elubrixin (SB-656933) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation[1][2][3].
Molekulargewicht:
463.31
CAS Nummer:
[688763-64-6]
Formel:
C17H17Cl2FN4O4S
Target-Kategorie:
CXCR,Interleukin Related
Anwendungsbeschreibung:
MCE Product type: Reference compound
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