BRD4/AKT-IN-1, CAS [[3087270-50-3]] Preis auf Anfrage
Artikelnummer:
MCE-HY-183273
Hersteller Artikelnummer:
HY-183273
Alternativnummer:
MCE-HY-183273-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
BRD4/AKT-IN-1 is a BRD4/AKT inhibitor with BRD4 IC50 66.12 nM and AKT1 IC50 143.81 nM. BRD4/AKT-IN-1 blocks BRD4-mediated c-Myc transcriptional regulation, modulates AKT1 signaling, decouples AKT phosphorylation from pro-survival effectors. BRD4/AKT-IN-1 induces G0/G1 cell cycle arrest via downregulated phosphorylated RB, cyclin E1, CDK2. BRD4/AKT-IN-1 elevates LC3B levels to promote autophagy. BRD4/AKT-IN-1 promotes apoptosis in cancer cells. BRD4/AKT-IN-1 can be used for the research of metastatic castration-resistant prostate cancer[1].
