(R)-CR8, CAS [[294646-77-8]]

Produktübersicht

• Artikelname: (R)-CR8, CAS [[294646-77-8]]
• Artikelnummer: MCE-HY-18340
• Hersteller Artikelnummer: HY-18340
• Alternativnummer: MCE-HY-18340-50MG,MCE-HY-18340-10MG,MCE-HY-18340-10MMX1ML,MCE-HY-18340-25MG,MCE-HY-18340-100MG,MCE-HY-18340-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CR8, (R)-Isomer

Produktbeschreibung

(R)-CR8, a second-generation analog of Roscovitine, is a potent CDK1/2/5/7/9 inhibitor. (R)-CR8 inhibits CDK1/cyclin B (IC50=0.09 µM), CDK2/cyclin A (0.072 µM), CDK2/cyclin E (0.041 µM), CDK5/p25 (0.11 µM), CDK7/cyclin H (1.1 µM), CDK9/cyclin T (0.18 µM) and CK1delta/epsilon (0.4 µM). (R)-CR8 induces apoptosis and has neuroprotective effect[1][2]. (R)-CR8 acts as a molecular glue degrader that depletes cyclin K[3].

Produkteigenschaften

• Molekulargewicht: 431.53
• Reinheit: 99.61
• CAS Nummer: [294646-77-8]
• Formel: C24H29N7O
• Target-Kategorie: Apoptosis,CDK,Molecular Glues

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound