AZ14289671, CAS [[3101563-22-5]]

Produktübersicht

• Artikelname: AZ14289671, CAS [[3101563-22-5]]
• Artikelnummer: MCE-HY-183682
• Hersteller Artikelnummer: HY-183682
• Alternativnummer: MCE-HY-183682-5MG, MCE-HY-183682-10MG, MCE-HY-183682-25MG, MCE-HY-183682-100MG, MCE-HY-183682-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

AZ14289671 is an orally active, blood-brain barrier-penetrant tyrosine kinase (tyrosine kinase) inhibitor (TKI) that specifically targets non-small cell lung cancer (NSCLC) harboring EGFR exon 20 insertion mutations (EGFRExon20Ins), while largely sparing wild-type EGFR to reduce off-target toxicities such as rash and diarrhea. AZ14289671 inhibits the downstream MAPK/ERK/AKT pathway, suppressing tumor cell proliferation, survival and migration. AZ14289671 can be used for NSCLC research[1].

Produkteigenschaften

• Molekulargewicht: 499.30
• CAS Nummer: [3101563-22-5]
• Formel: C23H14Cl2F2N6O
• Target-Kategorie: Akt,EGFR,ERK,p38 MAPK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound