Ferroptosis/apoptosis inducer-5, CAS [[2243423-32-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-183791A
Hersteller Artikelnummer:
HY-183791A
Alternativnummer:
MCE-HY-183791A-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Ferroptosis/apoptosis inducer-5 (Compound 14) is an orally active inducer of Ferroptosis and Apoptosis. Ferroptosis/apoptosis inducer-5 downregulates GPX4, upregulates ACSL4, promotes ROS production, activates the Caspase cascade, induces Mitochondrial dysfunction, and alters the Bcl-2/Bax balance. Ferroptosis/apoptosis inducer-5 significantly inhibits tumor growth in a pancreatic cancer xenograft mouse model. Ferroptosis/apoptosis inducer-5 can be used for the research of pancreatic cancer[1].
Molekulargewicht:
868.01
CAS Nummer:
[2243423-32-5]
Formel:
C53H72BrO3P
Target-Kategorie:
ACSL Family,Apoptosis,Bcl-2 Family,Caspase,Ferroptosis,Glutathione Peroxidase,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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