MC-AcLys-GDEVD-PABC-Exatecan Preis auf Anfrage

Produktübersicht

• Artikelname: MC-AcLys-GDEVD-PABC-Exatecan Preis auf Anfrage
• Artikelnummer: MCE-HY-185101
• Hersteller Artikelnummer: HY-185101
• Alternativnummer: MCE-HY-185101-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

MC-AcLys-GDEVD-PABC-Exatecan (MC-AcLys-GDEVD-PABC-DX8951) is a agent-linker conjugate for ADC. MC-AcLys-GDEVD-PABC-Exatecan is a DX8951 (a DNA topoisomerase I inhibitor) derivative with a novel caspase-3 cleavable peptide linker MC-AcLys-GDEVD-PABC linker. MC-AcLys-GDEVD-PABC-Exatecan can be used to prepare DX8951 antibody conjugate (ADC), and it exhibites significant bystander effect mediated by the caspase-3-triggered extracellular cleavage of the linker, enhancing payload release into the tumor microenvironment.

Produkteigenschaften

• Molekulargewicht: 1462.53
• Formel: C71H88FN13O20
• Target-Kategorie: Drug-Linker Conjugates for ADC

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: ADC Related