PF-04475270, CAS [[1201925-19-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-185643
Hersteller Artikelnummer:
HY-185643
Alternativnummer:
MCE-HY-185643-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
PF-04475270 is a prodrug of CP-734432 (HY-119236), as well as an agonist of the EP4 prostaglandin receptor, with IC50 values of 2 nM and 8 nM against human and canine sources, respectively. PF-04475270 is rapidly hydrolyzed into its active metabolite CP-734432 by ocular esterases or corneal homogenate, stimulates cAMP production, and activates cAMP response element-mediated beta-lactamase activity in cells expressing EP4. PF-04475270 can be used in research related to glaucoma[1][2].
