SRA-36 is a CLC-K chloride channel inhibitor with selectivity over CLC-5 and CLC-1 chloride channels. SRA-36 blocks CLC-Ka currents with an IC50 of 6.6 µM and a Kd of 3.8 µM. SRA-36 blocks chloride currents mediated by targeted channels, and inhibits currents from hypertension-associated CLC-KaA447T and CLC-KaY315F polymorphisms. SRA-36 can be used for the research of hypertension[1].
Molekulargewicht:
328.36
Formel:
C22H16O3
Target-Kategorie:
Chloride Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound
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