UMI-77-d4 is the deuterium labeled UMI-77. UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 µM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.
Molekulargewicht:
472.37
Formel:
C18H10D4BrNO5S2
Target-Kategorie:
Bcl-2 Family,Isotope-Labeled Compounds
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
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