Galidesivir (BCX4430), an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 µM[1][2][3].
Molekulargewicht:
265.27
Reinheit:
99.29
CAS Nummer:
[249503-25-1]
Formel:
C11H15N5O3
Target-Kategorie:
DNA/RNA Synthesis,Filovirus,SARS-CoV
Anwendungsbeschreibung:
MCE Product type: Reference compound
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