SIBA (5-Isobutylthioadenosine) is a transmethylation inhibitor (SAH (HY-19528) analogue), with potent anti-proliferative activity. SIBA reversibly inhibits the production of HSV-1 by blocking methylation, specifically by blocking the 5 end-capping of viral mRNA. SIBA also inhibits the growth of tumour cells in vitro and metastatic spread in vivo. SIBA can be used in cancer, HSV-1 infection and anti-malaria studies[1][2][3].
Molekulargewicht:
339.41
Reinheit:
99.64
CAS Nummer:
[35899-54-8]
Formel:
C14H21N5O3S
Target-Kategorie:
HSV,Nucleoside Antimetabolite/Analog,Parasite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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