Endoxifen (Z-isomer hydrochloride), CAS [[1032008-74-4]]
Artikelnummer:
MCE-HY-18719A
| Artikelname: |
Endoxifen (Z-isomer hydrochloride), CAS [[1032008-74-4]] |
| Artikelnummer: |
MCE-HY-18719A |
| Hersteller Artikelnummer: |
HY-18719A |
| Alternativnummer: |
MCE-HY-18719A-10MMX1ML,MCE-HY-18719A-5MG,MCE-HY-18719A-10MG |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| Endoxifen Z-isomer hydrochloride, an orally active Tamoxifen (HY-13757A) metabolite, is a selective estrogen receptor modulator with 100-fold more potency than its parent agent, Tamoxifen. Endoxifen Z-isomer hydrochloride inhibits PKCbeta1 kinase activity. Endoxifen Z-isomer hydrochloride attenuates PKCbeta1-activated AKTSer473 phosphorylation, diminishes AKT substrate phosphorylation, and induces Apoptosis. Endoxifen Z-isomer hydrochloride exhibits anticancer activity against hormone-resistant metastatic breast cancer[1][2][3][4]. |
| Molekulargewicht: |
409.95 |
| Reinheit: |
99.67 |
| CAS Nummer: |
[1032008-74-4] |
| Formel: |
C25H28ClNO2 |
| Target-Kategorie: |
Akt,Apoptosis,Drug Metabolite,Estrogen Receptor/ERR,PKC |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
