R-03201195 is an efficient and selective p38 MAP kinase inhibitor with an IC50 for p38alpha of 0.7 nM. R-03201195 has inhibitory activity against TNF-alpha in THP-1 cells and against IL-1beta in human whole blood, with IC50 values of 0.25 and 0.57 nM respectively. R-03201195 can be used for inflammatory diseases such as rheumatoid arthritis[1].
Molekulargewicht:
371.36
CAS Nummer:
[249936-55-8]
Formel:
C19H18FN3O4
Target-Kategorie:
Interleukin Related,p38 MAPK,TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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