mTOR inhibitor-23 (compound DHM25) is a selective, competitive, irreversible and covalent inhibitor of mTOR. mTOR inhibitor-23 has the mechanism of inhibition occurs mainly through its capacity to covalently interact with a nucleophilic amino acid inside the ATP pocket. mTOR inhibitor-23 exerts potent antitumor activity against triple-negative breast tumor cell lines[1].
Molekulargewicht:
489.94
CAS Nummer:
[1685280-21-0]
Formel:
C15H8Br3NO3
Target-Kategorie:
mTOR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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