ADD-17014 is a L-Glu antagonist. ADD-17014 impairs presynaptic excitatory amino acid L-Glu neurotransmission. ADD-17014 is a prodrug of its beta-amino alcohol metabolite, and the metabolite acts as a NMDA receptor antagonist by binding to the MK-801 site located inside the NMDA receptor or ion channel. ADD-17014 has an anticonvulsant and anti-ischemic activity. ADD-17014 can be used for neurodegenerative diseases like Parkinsons disease, Alzheimers disease and stroke research[1][2].
Molekulargewicht:
258.71
CAS Nummer:
[55643-87-3]
Formel:
C13H11ClN4
Target-Kategorie:
mGluR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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