DuP-532 is an angiotensin type 1 receptor antagonist with potential activity in the suppression of hypertension and heart failure. DuP-532 can react with a range of aryl and heteroaryl halides to form perfluoroalkyl(hetero)arenes in moderate to high yields. Computational studies of DuP-532 suggest that coordination of a second phenyl ring ligand may lower the energy barrier for decarboxylation of perfluorocarboxylates, thereby promoting the perfluoroalkylation reaction[1].
Molekulargewicht:
506.43
Reinheit:
98.00
CAS Nummer:
[124750-95-4]
Formel:
C23H19F5N6O2
Target-Kategorie:
Angiotensin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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