WDR5-0103 (WD-Repeat Protein 5-0103) is a potent and selective WD repeat-containing protein 5 (WDR5) antagonist with a Kd of 450 nM. WDR5-0103 competitively binds to the peptide-binding pocket of WDR5, blocking the interaction between WDR5 and mixed-lineage leukemia (MLL) protein and inhibiting the methyltransferase activity of MLL. WDR5-0103 is mainly used in the research of cancer and neurodegenerative diseases[1][2][3].
Molekulargewicht:
383.44
Reinheit:
99.94
CAS Nummer:
[890190-22-4]
Formel:
C21H25N3O4
Target-Kategorie:
WDR5
Anwendungsbeschreibung:
MCE Product type: Reference compound
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