Branaplam (hydrochloride), CAS [[1562338-39-9]]

Produktübersicht

• Artikelname: Branaplam (hydrochloride), CAS [[1562338-39-9]]
• Artikelnummer: MCE-HY-19620A
• Hersteller Artikelnummer: HY-19620A
• Alternativnummer: MCE-HY-19620A-10MG,MCE-HY-19620A-10MMX1ML,MCE-HY-19620A-100MG,MCE-HY-19620A-50MG,MCE-HY-19620A-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: LMI070 (hydrochloride), NVS-SM1 (hydrochloride)

Produktbeschreibung

Branaplam (LMI070, NVS-SM1) hydrochloride is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 µM. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model[1][2].

Produkteigenschaften

• Molekulargewicht: 429.94
• Reinheit: 99.43
• CAS Nummer: [1562338-39-9]
• Formel: C22H28ClN5O2
• Target-Kategorie: DNA/RNA Synthesis,Potassium Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound