Sitamaquine (WR6026) tosylate, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine tosylate inhibits mitochondrial complex II (succinate dehydrogenase). Sitamaquine tosylate is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes[1][2].
Molekulargewicht:
515.71
CAS Nummer:
[1019640-33-5]
Formel:
C28H41N3O4S
Target-Kategorie:
Mitochondrial Metabolism,Parasite
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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